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Active ingredient: Each capsule (Tablet) contents
Indication & Dosage
Adjunct to treatment of Pneumocystis carinii pneumonia
Adult: >13 yr and with AIDS: 40 mg bid for 5 days followed by 40 mg once daily for 5 days, then 20 mg once daily for 11 days or until completion of the anti-infective regimen. Should be initiated within 24-72 hr of initial antipneumocystis therapy.
Should be taken with food.
Hypersensitivity, serious infections (except tuberculous meningitis), varicella, systemic fungal infections. Pregnancy and lactation.
Osteoporosis, hypertension, diabetes mellitus, epilepsy, glaucoma, cataracts, tuberculosis, hypothyroidism, cirrhosis, CHF, ulcerative colitis, throboembolic disorders, peptic ulcer disease, hepatic impairment. Elderly; child (may retard bone growth). withdraw therapy with a gradual tapering of dose.
Adverse Drug Reactions
Insomnia, nervousness, increased appetite, indigestion, dizziness/lightheadedness, headache, hirsutism, hypopigmentation, diabetes mellitus, glucose intolerance, hyperglycaemia, arthralgia, cataracts, glaucoma, epistaxis, diaphoresis, Cushing's syndrome, edema, fractures, hallucinations, hypertension, muscle-wasting, osteoporosis, pancreatitis, pituitary-adrenal axis suppression, seizures.
Substrate of CYP3A4; induces CYP2C19, 3A4. Increased risk of GI ulceration with NSAIDs. Decreased effect with barbiturates, phenytoin, rifampin. Decreased effect of salicylates, vaccines and toxoids. Ethanol may increase gastric mucosal irritation.
Mechanism of Action
Prednisone is biologically inert and converted to the predominantly prednisolone in the liver. It decreases inflammation by suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability; suppresses the immune system by reducing activity and vol of the lymphatic system; suppresses adrenal function at high doses. Indications and dosage are same as those for prednisolone.
A07EA03 - Prednisone; Belongs to the class of corticosteroids acting locally. Used in the treatment of intestinal inflammation.
H02AB07 - Prednisone; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.
Shelf life: 36 months
Box of 1 bottle x 200 caps
Box of 1 bottle x 500 tabs
For further information please contact us:
Manufacturer: Thanh Nam Pharmaceutical Production Trading Company Ltd.
Address: 60 – Doc Lap Avenue, Vietnam Singapore Industry Park
Thuan An, Bình Dương
Office: 3A Dang Tat Street, Tan Dinh ward, district 1
HCM city, Vietnam
Telephone : (+84650) – 3767850 Fax : (+84650) – 3767852